High-depth African genomes inform human migration and health
Identifieur interne : 000738 ( Main/Exploration ); précédent : 000737; suivant : 000739High-depth African genomes inform human migration and health
Auteurs : Ananyo Choudhury [Afrique du Sud] ; Shaun Aron [Afrique du Sud] ; Laura R. Botigué [Espagne] ; Dhriti Sengupta [Afrique du Sud] ; Gerrit Botha [Afrique du Sud] ; Taoufik Bensellak [Maroc] ; Gordon Wells [Afrique du Sud] ; Judit Kumuthini [Afrique du Sud] ; Daniel Shriner [États-Unis] ; Yasmina J. Fakim ; Anisah W. Ghoorah ; Eileen Dareng [Royaume-Uni, Nigeria] ; Trust Odia [Nigeria] ; Oluwadamilare Falola [Nigeria] ; Ezekiel Adebiyi [Nigeria] ; Scott Hazelhurst [Afrique du Sud] ; Gaston Mazandu [Afrique du Sud] ; Oscar A. Nyangiri [Ouganda] ; Mamana Mbiyavanga [Afrique du Sud] ; Alia Benkahla [Tunisie] ; Samar K. Kassim [Égypte] ; Nicola Mulder [Afrique du Sud] ; Sally N. Adebamowo [États-Unis] ; Emile R. Chimusa [Afrique du Sud] ; Donna Muzny [États-Unis] ; Ginger Metcalf [États-Unis] ; Richard A. Gibbs [États-Unis] ; Charles Rotimi [États-Unis] ; Michèle Ramsay [Afrique du Sud] ; Adebowale A. Adeyemo [États-Unis] ; Zané Lombard [Afrique du Sud] ; Neil A. HanchardSource :
- Nature [ 0028-0836 ] ; 2020.
Descripteurs français
- KwdFr :
- Afrique (ethnologie), Femelle (MeSH), Flux des gènes (MeSH), Génome humain (génétique), Génomique (MeSH), Génétique des populations (MeSH), Génétique médicale (MeSH), Histoire ancienne (MeSH), Humains (MeSH), Immunité (génétique), Jeux de données comme sujet (MeSH), Langage (MeSH), Migration humaine (histoire), Mâle (MeSH), Métabolisme (génétique), Réparation de l'ADN (génétique), Santé (histoire), Sélection génétique (MeSH), Séquençage du génome entier (MeSH), Variation génétique (MeSH).
- MESH :
- ethnologie : Afrique.
- génétique : Génome humain, Immunité, Métabolisme, Réparation de l'ADN.
- histoire : Migration humaine, Santé.
- Femelle, Flux des gènes, Génomique, Génétique des populations, Génétique médicale, Histoire ancienne, Humains, Jeux de données comme sujet, Langage, Mâle, Sélection génétique, Séquençage du génome entier, Variation génétique.
English descriptors
- KwdEn :
- Africa (ethnology), DNA Repair (genetics), Datasets as Topic (MeSH), Female (MeSH), Gene Flow (MeSH), Genetic Variation (MeSH), Genetics, Medical (MeSH), Genetics, Population (MeSH), Genome, Human (genetics), Genomics (MeSH), Health (history), History, Ancient (MeSH), Human Migration (history), Humans (MeSH), Immunity (genetics), Language (MeSH), Male (MeSH), Metabolism (genetics), Selection, Genetic (MeSH), Whole Genome Sequencing (MeSH).
- MESH :
- geographic , ethnology : Africa.
- genetics : DNA Repair, Genome, Human, Immunity, Metabolism.
- history : Health, Human Migration.
- Datasets as Topic, Female, Gene Flow, Genetic Variation, Genetics, Medical, Genetics, Population, Genomics, History, Ancient, Humans, Language, Male, Selection, Genetic, Whole Genome Sequencing.
Abstract
The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the genetic diversity among African individuals has been surveyed
Url:
DOI: 10.1038/s41586-020-2859-7
PubMed: 33116287
PubMed Central: 7759466
Affiliations:
- Afrique du Sud, Espagne, Maroc, Nigeria, Ouganda, Royaume-Uni, Tunisie, Égypte, États-Unis
- Maryland, Texas
Links toward previous steps (curation, corpus...)
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- to stream Pmc, to step Checkpoint: 000061
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- to stream PubMed, to step Curation: 000084
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- to stream Main, to step Merge: 000738
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Le document en format XML
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Hanchard</name><affiliation><nlm:aff id="Aff22"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Department of Molecular and Human Genetics,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, Texas USA</nlm:aff><wicri:noCountry code="subfield">Texas USA</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">33116287</idno><idno type="pmc">7759466</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759466</idno><idno type="RBID">PMC:7759466</idno><idno type="doi">10.1038/s41586-020-2859-7</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000067</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000067</idno><idno type="wicri:Area/Pmc/Curation">000067</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000067</idno><idno type="wicri:Area/Pmc/Checkpoint">000061</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000061</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:33116287</idno><idno type="wicri:Area/PubMed/Corpus">000085</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000085</idno><idno type="wicri:Area/PubMed/Curation">000084</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000084</idno><idno type="wicri:Area/PubMed/Checkpoint">000134</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000134</idno><idno type="wicri:Area/Main/Merge">000738</idno><idno type="wicri:Area/Main/Curation">000738</idno><idno type="wicri:Area/Main/Exploration">000738</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">High-depth African genomes inform human migration and health</title><author><name sortKey="Choudhury, Ananyo" sort="Choudhury, Ananyo" uniqKey="Choudhury A" first="Ananyo" last="Choudhury">Ananyo Choudhury</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Aron, Shaun" sort="Aron, Shaun" uniqKey="Aron S" first="Shaun" last="Aron">Shaun Aron</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Botigue, Laura R" sort="Botigue, Laura R" uniqKey="Botigue L" first="Laura R." last="Botigué">Laura R. Botigué</name><affiliation wicri:level="1"><nlm:aff id="Aff2">Center for Research in Agricultural Genomics (CRAG), Plant and Animal Genomics Program, CSIC-IRTA-UAB-UB, Barcelona, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Center for Research in Agricultural Genomics (CRAG), Plant and Animal Genomics Program, CSIC-IRTA-UAB-UB, Barcelona</wicri:regionArea></affiliation></author><author><name sortKey="Sengupta, Dhriti" sort="Sengupta, Dhriti" uniqKey="Sengupta D" first="Dhriti" last="Sengupta">Dhriti Sengupta</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Botha, Gerrit" sort="Botha, Gerrit" uniqKey="Botha G" first="Gerrit" last="Botha">Gerrit Botha</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1151</institution-id><institution-id institution-id-type="GRID">grid.7836.a</institution-id><institution>Computational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences,</institution><institution>IDM, University of Cape Town,</institution></institution-wrap>Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Bensellak, Taoufik" sort="Bensellak, Taoufik" uniqKey="Bensellak T" first="Taoufik" last="Bensellak">Taoufik Bensellak</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0675 7133</institution-id><institution-id institution-id-type="GRID">grid.251700.1</institution-id><institution>System and Data Engineering Team,</institution><institution>Abdelmalek Essaadi University, ENSA,</institution></institution-wrap>Tangier, Morocco</nlm:aff><country xml:lang="fr">Maroc</country><wicri:regionArea>Tangier</wicri:regionArea></affiliation></author><author><name sortKey="Wells, Gordon" sort="Wells, Gordon" uniqKey="Wells G" first="Gordon" last="Wells">Gordon Wells</name><affiliation wicri:level="1"><nlm:aff id="Aff5">Centre for Proteomic and Genomic Research (CPGR), Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for Proteomic and Genomic Research (CPGR), Cape Town</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff6"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2156 8226</institution-id><institution-id institution-id-type="GRID">grid.8974.2</institution-id><institution>South African National Bioinformatics Network,</institution><institution>University of the Western Cape,</institution></institution-wrap>Bellville, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Bellville</wicri:regionArea></affiliation></author><author><name sortKey="Kumuthini, Judit" sort="Kumuthini, Judit" uniqKey="Kumuthini J" first="Judit" last="Kumuthini">Judit Kumuthini</name><affiliation wicri:level="1"><nlm:aff id="Aff5">Centre for Proteomic and Genomic Research (CPGR), Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for Proteomic and Genomic Research (CPGR), Cape Town</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff6"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2156 8226</institution-id><institution-id institution-id-type="GRID">grid.8974.2</institution-id><institution>South African National Bioinformatics Network,</institution><institution>University of the Western Cape,</institution></institution-wrap>Bellville, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Bellville</wicri:regionArea></affiliation></author><author><name sortKey="Shriner, Daniel" sort="Shriner, Daniel" uniqKey="Shriner D" first="Daniel" last="Shriner">Daniel Shriner</name><affiliation wicri:level="2"><nlm:aff id="Aff7"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2233 9230</institution-id><institution-id institution-id-type="GRID">grid.280128.1</institution-id><institution>Center for Research on Genomics and Global Health,</institution><institution>National Human Genome Research Institute, National Institutes of Health,</institution></institution-wrap>Bethesda, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Fakim, Yasmina J" sort="Fakim, Yasmina J" uniqKey="Fakim Y" first="Yasmina J." last="Fakim">Yasmina J. 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Cambridge,</institution></institution-wrap>Cambridge, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cambridge</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff11"><institution-wrap><institution-id institution-id-type="GRID">grid.421160.0</institution-id><institution>Institute of Human Virology Nigeria,</institution></institution-wrap>Abuja, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Abuja</wicri:regionArea></affiliation></author><author><name sortKey="Odia, Trust" sort="Odia, Trust" uniqKey="Odia T" first="Trust" last="Odia">Trust Odia</name><affiliation wicri:level="1"><nlm:aff id="Aff12"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1794 8359</institution-id><institution-id institution-id-type="GRID">grid.411932.c</institution-id><institution>Covenant University Bioinformatics Research (CUBRe),</institution><institution>Covenant University,</institution></institution-wrap>Ota, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Ota</wicri:regionArea></affiliation></author><author><name sortKey="Falola, Oluwadamilare" sort="Falola, Oluwadamilare" uniqKey="Falola O" first="Oluwadamilare" last="Falola">Oluwadamilare Falola</name><affiliation wicri:level="1"><nlm:aff id="Aff12"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1794 8359</institution-id><institution-id institution-id-type="GRID">grid.411932.c</institution-id><institution>Covenant University Bioinformatics Research (CUBRe),</institution><institution>Covenant University,</institution></institution-wrap>Ota, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Ota</wicri:regionArea></affiliation></author><author><name sortKey="Adebiyi, Ezekiel" sort="Adebiyi, Ezekiel" uniqKey="Adebiyi E" first="Ezekiel" last="Adebiyi">Ezekiel Adebiyi</name><affiliation wicri:level="1"><nlm:aff id="Aff12"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1794 8359</institution-id><institution-id institution-id-type="GRID">grid.411932.c</institution-id><institution>Covenant University Bioinformatics Research (CUBRe),</institution><institution>Covenant University,</institution></institution-wrap>Ota, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Ota</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff13"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1794 8359</institution-id><institution-id institution-id-type="GRID">grid.411932.c</institution-id><institution>Department of Computer and Information Sciences,</institution><institution>Covenant University,</institution></institution-wrap>Ota, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Ota</wicri:regionArea></affiliation></author><author><name sortKey="Hazelhurst, Scott" sort="Hazelhurst, Scott" uniqKey="Hazelhurst S" first="Scott" last="Hazelhurst">Scott Hazelhurst</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff14"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>School of Electrical and Information Engineering,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Mazandu, Gaston" sort="Mazandu, Gaston" uniqKey="Mazandu G" first="Gaston" last="Mazandu">Gaston Mazandu</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1151</institution-id><institution-id institution-id-type="GRID">grid.7836.a</institution-id><institution>Computational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences,</institution><institution>IDM, University of Cape Town,</institution></institution-wrap>Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Nyangiri, Oscar A" sort="Nyangiri, Oscar A" uniqKey="Nyangiri O" first="Oscar A." last="Nyangiri">Oscar A. Nyangiri</name><affiliation wicri:level="1"><nlm:aff id="Aff15"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0620 0548</institution-id><institution-id institution-id-type="GRID">grid.11194.3c</institution-id><institution>College of Veterinary Medicine, Animal Resources and Biosecurity,</institution><institution>Makerere University,</institution></institution-wrap>Kampala, Uganda</nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea>Kampala</wicri:regionArea></affiliation></author><author><name sortKey="Mbiyavanga, Mamana" sort="Mbiyavanga, Mamana" uniqKey="Mbiyavanga M" first="Mamana" last="Mbiyavanga">Mamana Mbiyavanga</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1151</institution-id><institution-id institution-id-type="GRID">grid.7836.a</institution-id><institution>Computational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences,</institution><institution>IDM, University of Cape Town,</institution></institution-wrap>Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Benkahla, Alia" sort="Benkahla, Alia" uniqKey="Benkahla A" first="Alia" last="Benkahla">Alia Benkahla</name><affiliation wicri:level="1"><nlm:aff id="Aff16">Laboratory of Bioinformatics, Biomathematics and Biostatistics (BIMS), Institute Pasteur of Tunis, Tunis, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Laboratory of Bioinformatics, Biomathematics and Biostatistics (BIMS), Institute Pasteur of Tunis, Tunis</wicri:regionArea></affiliation></author><author><name sortKey="Kassim, Samar K" sort="Kassim, Samar K" uniqKey="Kassim S" first="Samar K." last="Kassim">Samar K. Kassim</name><affiliation wicri:level="1"><nlm:aff id="Aff17"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0621 1570</institution-id><institution-id institution-id-type="GRID">grid.7269.a</institution-id><institution>Medical Biochemistry and Molecular Biology Department, Faculty of Medicine,</institution><institution>Ain Shams University, Abbaseya,</institution></institution-wrap>Cairo, Egypt</nlm:aff><country xml:lang="fr">Égypte</country><wicri:regionArea>Cairo</wicri:regionArea></affiliation></author><author><name sortKey="Mulder, Nicola" sort="Mulder, Nicola" uniqKey="Mulder N" first="Nicola" last="Mulder">Nicola Mulder</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1151</institution-id><institution-id institution-id-type="GRID">grid.7836.a</institution-id><institution>Computational Biology Division and H3ABioNet, Department of Integrative Biomedical Sciences,</institution><institution>IDM, University of Cape Town,</institution></institution-wrap>Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Adebamowo, Sally N" sort="Adebamowo, Sally N" uniqKey="Adebamowo S" first="Sally N." last="Adebamowo">Sally N. Adebamowo</name><affiliation wicri:level="2"><nlm:aff id="Aff18"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2175 4264</institution-id><institution-id institution-id-type="GRID">grid.411024.2</institution-id><institution>Department of Epidemiology and Public Health, University of Maryland School of Medicine,</institution><institution>University of Maryland Baltimore,</institution></institution-wrap>Baltimore, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Baltimore</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="Aff19"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2175 4264</institution-id><institution-id institution-id-type="GRID">grid.411024.2</institution-id><institution>University of Maryland Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine,</institution><institution>University of Maryland Baltimore,</institution></institution-wrap>Baltimore, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Baltimore</wicri:cityArea></affiliation></author><author><name sortKey="Chimusa, Emile R" sort="Chimusa, Emile R" uniqKey="Chimusa E" first="Emile R." last="Chimusa">Emile R. Chimusa</name><affiliation wicri:level="1"><nlm:aff id="Aff20"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1151</institution-id><institution-id institution-id-type="GRID">grid.7836.a</institution-id><institution>Division of Human Genetics, Department of Pathology, Faculty of Health Sciences, Institute for Infectious, Disease and Molecular Medicine,</institution><institution>University of Cape Town,</institution></institution-wrap>Cape Town, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Cape Town</wicri:regionArea></affiliation></author><author><name sortKey="Muzny, Donna" sort="Muzny, Donna" uniqKey="Muzny D" first="Donna" last="Muzny">Donna Muzny</name><affiliation wicri:level="2"><nlm:aff id="Aff21"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Human Genome Sequencing Center,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, TX USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Houston</wicri:cityArea></affiliation></author><author><name sortKey="Metcalf, Ginger" sort="Metcalf, Ginger" uniqKey="Metcalf G" first="Ginger" last="Metcalf">Ginger Metcalf</name><affiliation wicri:level="2"><nlm:aff id="Aff21"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Human Genome Sequencing Center,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, TX USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Houston</wicri:cityArea></affiliation></author><author><name sortKey="Gibbs, Richard A" sort="Gibbs, Richard A" uniqKey="Gibbs R" first="Richard A." last="Gibbs">Richard A. Gibbs</name><affiliation wicri:level="2"><nlm:aff id="Aff21"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Human Genome Sequencing Center,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, TX USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Houston</wicri:cityArea></affiliation><affiliation><nlm:aff id="Aff22"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Department of Molecular and Human Genetics,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, Texas USA</nlm:aff><wicri:noCountry code="subfield">Texas USA</wicri:noCountry></affiliation></author><author><name sortKey="Rotimi, Charles" sort="Rotimi, Charles" uniqKey="Rotimi C" first="Charles" last="Rotimi">Charles Rotimi</name><affiliation wicri:level="2"><nlm:aff id="Aff7"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2233 9230</institution-id><institution-id institution-id-type="GRID">grid.280128.1</institution-id><institution>Center for Research on Genomics and Global Health,</institution><institution>National Human Genome Research Institute, National Institutes of Health,</institution></institution-wrap>Bethesda, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Ramsay, Michele" sort="Ramsay, Michele" uniqKey="Ramsay M" first="Michèle" last="Ramsay">Michèle Ramsay</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff23"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Division of Human Genetics, National Health Laboratory Service, and School of Pathology, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Adeyemo, Adebowale A" sort="Adeyemo, Adebowale A" uniqKey="Adeyemo A" first="Adebowale A." last="Adeyemo">Adebowale A. Adeyemo</name><affiliation wicri:level="2"><nlm:aff id="Aff7"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2233 9230</institution-id><institution-id institution-id-type="GRID">grid.280128.1</institution-id><institution>Center for Research on Genomics and Global Health,</institution><institution>National Human Genome Research Institute, National Institutes of Health,</institution></institution-wrap>Bethesda, MD USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Lombard, Zane" sort="Lombard, Zane" uniqKey="Lombard Z" first="Zané" last="Lombard">Zané Lombard</name><affiliation wicri:level="1"><nlm:aff id="Aff23"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1937 1135</institution-id><institution-id institution-id-type="GRID">grid.11951.3d</institution-id><institution>Division of Human Genetics, National Health Laboratory Service, and School of Pathology, Faculty of Health Sciences,</institution><institution>University of the Witwatersrand,</institution></institution-wrap>Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Johannesburg</wicri:regionArea></affiliation></author><author><name sortKey="Hanchard, Neil A" sort="Hanchard, Neil A" uniqKey="Hanchard N" first="Neil A." last="Hanchard">Neil A. Hanchard</name><affiliation><nlm:aff id="Aff22"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 2160 926X</institution-id><institution-id institution-id-type="GRID">grid.39382.33</institution-id><institution>Department of Molecular and Human Genetics,</institution><institution>Baylor College of Medicine,</institution></institution-wrap>Houston, Texas USA</nlm:aff><wicri:noCountry code="subfield">Texas USA</wicri:noCountry></affiliation></author></analytic><series><title level="j">Nature</title><idno type="ISSN">0028-0836</idno><idno type="eISSN">1476-4687</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Africa (ethnology)</term><term>DNA Repair (genetics)</term><term>Datasets as Topic (MeSH)</term><term>Female (MeSH)</term><term>Gene Flow (MeSH)</term><term>Genetic Variation (MeSH)</term><term>Genetics, Medical (MeSH)</term><term>Genetics, Population (MeSH)</term><term>Genome, Human (genetics)</term><term>Genomics (MeSH)</term><term>Health (history)</term><term>History, Ancient (MeSH)</term><term>Human Migration (history)</term><term>Humans (MeSH)</term><term>Immunity (genetics)</term><term>Language (MeSH)</term><term>Male (MeSH)</term><term>Metabolism (genetics)</term><term>Selection, Genetic (MeSH)</term><term>Whole Genome Sequencing (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Afrique (ethnologie)</term><term>Femelle (MeSH)</term><term>Flux des gènes (MeSH)</term><term>Génome humain (génétique)</term><term>Génomique (MeSH)</term><term>Génétique des populations (MeSH)</term><term>Génétique médicale (MeSH)</term><term>Histoire ancienne (MeSH)</term><term>Humains (MeSH)</term><term>Immunité (génétique)</term><term>Jeux de données comme sujet (MeSH)</term><term>Langage (MeSH)</term><term>Migration humaine (histoire)</term><term>Mâle (MeSH)</term><term>Métabolisme (génétique)</term><term>Réparation de l'ADN (génétique)</term><term>Santé (histoire)</term><term>Sélection génétique (MeSH)</term><term>Séquençage du génome entier (MeSH)</term><term>Variation génétique (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="ethnology" xml:lang="en"><term>Africa</term></keywords><keywords scheme="MESH" qualifier="ethnologie" xml:lang="fr"><term>Afrique</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>DNA Repair</term><term>Genome, Human</term><term>Immunity</term><term>Metabolism</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Génome humain</term><term>Immunité</term><term>Métabolisme</term><term>Réparation de l'ADN</term></keywords><keywords scheme="MESH" qualifier="histoire" xml:lang="fr"><term>Migration humaine</term><term>Santé</term></keywords><keywords scheme="MESH" qualifier="history" xml:lang="en"><term>Health</term><term>Human Migration</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Datasets as Topic</term><term>Female</term><term>Gene Flow</term><term>Genetic Variation</term><term>Genetics, Medical</term><term>Genetics, Population</term><term>Genomics</term><term>History, Ancient</term><term>Humans</term><term>Language</term><term>Male</term><term>Selection, Genetic</term><term>Whole Genome Sequencing</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Femelle</term><term>Flux des gènes</term><term>Génomique</term><term>Génétique des populations</term><term>Génétique médicale</term><term>Histoire ancienne</term><term>Humains</term><term>Jeux de données comme sujet</term><term>Langage</term><term>Mâle</term><term>Sélection génétique</term><term>Séquençage du génome entier</term><term>Variation génétique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">The African continent is regarded as the cradle of modern humans and African genomes contain more genetic variation than those from any other continent, yet only a fraction of the genetic diversity among African individuals has been surveyed<sup><xref ref-type="bibr" rid="CR1">1</xref></sup>. Here we performed whole-genome sequencing analyses of 426 individuals—comprising 50 ethnolinguistic groups, including previously unsampled populations—to explore the breadth of genomic diversity across Africa. We uncovered more than 3 million previously undescribed variants, most of which were found among individuals from newly sampled ethnolinguistic groups, as well as 62 previously unreported loci that are under strong selection, which were predominantly found in genes that are involved in viral immunity, DNA repair and metabolism. We observed complex patterns of ancestral admixture and putative-damaging and novel variation, both within and between populations, alongside evidence that Zambia was a likely intermediate site along the routes of expansion of Bantu-speaking populations. Pathogenic variants in genes that are currently characterized as medically relevant were uncommon—but in other genes, variants denoted as ‘likely pathogenic’ in the ClinVar database were commonly observed. Collectively, these findings refine our current understanding of continental migration, identify gene flow and the response to human disease as strong drivers of genome-level population variation, and underscore the scientific imperative for a broader characterization of the genomic diversity of African individuals to understand human ancestry and improve health.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Nielsen, R" uniqKey="Nielsen R">R Nielsen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tishkoff, Sa" uniqKey="Tishkoff S">SA Tishkoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gurdasani, D" uniqKey="Gurdasani D">D Gurdasani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lek, M" uniqKey="Lek M">M Lek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Posey, Je" uniqKey="Posey J">JE Posey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Landry, Lg" uniqKey="Landry L">LG Landry</name></author><author><name sortKey="Ali, N" uniqKey="Ali N">N Ali</name></author><author><name sortKey="Williams, Dr" uniqKey="Williams D">DR Williams</name></author><author><name sortKey="Rehm, Hl" uniqKey="Rehm H">HL Rehm</name></author><author><name sortKey="Bonham, Vl" uniqKey="Bonham V">VL Bonham</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Patin, E" uniqKey="Patin E">E Patin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hanchard, N" uniqKey="Hanchard N">N Hanchard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ranciaro, A" uniqKey="Ranciaro A">A Ranciaro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Genovese, G" uniqKey="Genovese G">G Genovese</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabeti, Pc" uniqKey="Sabeti P">PC Sabeti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schlebusch, Cm" uniqKey="Schlebusch C">CM Schlebusch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scheinfeldt, Lb" uniqKey="Scheinfeldt L">LB Scheinfeldt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skoglund, P" uniqKey="Skoglund P">P Skoglund</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choudhury, A" uniqKey="Choudhury A">A Choudhury</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ilboudo, H" uniqKey="Ilboudo H">H Ilboudo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alexander, Dh" uniqKey="Alexander D">DH Alexander</name></author><author><name sortKey="Novembre, J" uniqKey="Novembre J">J Novembre</name></author><author><name sortKey="Lange, K" uniqKey="Lange K">K Lange</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patterson, N" uniqKey="Patterson N">N Patterson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semo, A" uniqKey="Semo A">A Semo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loh, P R" uniqKey="Loh P">P-R Loh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patin, E" uniqKey="Patin E">E Patin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shriner, D" uniqKey="Shriner D">D Shriner</name></author><author><name sortKey="Rotimi, Cn" uniqKey="Rotimi C">CN Rotimi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campbell, Im" uniqKey="Campbell I">IM Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campbell, Mc" uniqKey="Campbell M">MC Campbell</name></author><author><name sortKey="Tishkoff, Sa" uniqKey="Tishkoff S">SA Tishkoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pavlidis, P" uniqKey="Pavlidis P">P Pavlidis</name></author><author><name sortKey="Zivkovic, D" uniqKey="Zivkovic D">D Živkovic</name></author><author><name sortKey="Stamatakis, A" uniqKey="Stamatakis A">A Stamatakis</name></author><author><name sortKey="Alachiotis, N" uniqKey="Alachiotis N">N Alachiotis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szpiech, Za" uniqKey="Szpiech Z">ZA Szpiech</name></author><author><name sortKey="Hernandez, Rd" uniqKey="Hernandez R">RD Hernandez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vitti, Jj" uniqKey="Vitti J">JJ Vitti</name></author><author><name sortKey="Grossman, Sr" uniqKey="Grossman S">SR Grossman</name></author><author><name sortKey="Sabeti, Pc" uniqKey="Sabeti P">PC Sabeti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yi, X" uniqKey="Yi X">X Yi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Retshabile, G" uniqKey="Retshabile G">G Retshabile</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lim, Et" uniqKey="Lim E">ET Lim</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kalia, Ss" uniqKey="Kalia S">SS Kalia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manjurano, A" uniqKey="Manjurano A">A Manjurano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Howes, Re" uniqKey="Howes R">RE Howes</name></author><author><name sortKey="Battle, Ke" uniqKey="Battle K">KE Battle</name></author><author><name sortKey="Satyagraha, Aw" uniqKey="Satyagraha A">AW Satyagraha</name></author><author><name sortKey="Baird, Jk" uniqKey="Baird J">JK Baird</name></author><author><name sortKey="Hay, Si" uniqKey="Hay S">SI Hay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kimuda, Mp" uniqKey="Kimuda M">MP Kimuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rotimi, Cn" uniqKey="Rotimi C">CN Rotimi</name></author><author><name sortKey="Jorde, Lb" uniqKey="Jorde L">LB Jorde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Phillipson, Dw" uniqKey="Phillipson D">DW Phillipson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schlebusch, Cm" uniqKey="Schlebusch C">CM Schlebusch</name></author><author><name sortKey="Jakobsson, M" uniqKey="Jakobsson M">M Jakobsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mulindwa, J" uniqKey="Mulindwa J">J Mulindwa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shiroya, Oje" uniqKey="Shiroya O">OJE Shiroya</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Durbin, R" uniqKey="Durbin R">R Durbin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mckenna, A" uniqKey="Mckenna A">A McKenna</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Onnell, J" uniqKey="O Onnell J">J O’Connell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loh, Pr" uniqKey="Loh P">PR Loh</name></author><author><name sortKey="Palamara, Pf" uniqKey="Palamara P">PF Palamara</name></author><author><name sortKey="Price, Al" uniqKey="Price A">AL Price</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chang, Cc" uniqKey="Chang C">CC Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Patterson, N" uniqKey="Patterson N">N Patterson</name></author><author><name sortKey="Price, Al" uniqKey="Price A">AL Price</name></author><author><name sortKey="Reich, D" uniqKey="Reich D">D Reich</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Jakobsson, M" uniqKey="Jakobsson M">M Jakobsson</name></author><author><name sortKey="Rosenberg, Na" uniqKey="Rosenberg N">NA Rosenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, C" uniqKey="Wang C">C Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pickrell, Jk" uniqKey="Pickrell J">JK Pickrell</name></author><author><name sortKey="Pritchard, Jk" uniqKey="Pritchard J">JK Pritchard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pickrell, Jk" uniqKey="Pickrell J">JK Pickrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Browning, Bl" uniqKey="Browning B">BL Browning</name></author><author><name sortKey="Browning, Sr" uniqKey="Browning S">SR Browning</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atzmon, G" uniqKey="Atzmon G">G Atzmon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maples, Bk" uniqKey="Maples B">BK Maples</name></author><author><name sortKey="Gravel, S" uniqKey="Gravel S">S Gravel</name></author><author><name sortKey="Kenny, Ee" uniqKey="Kenny E">EE Kenny</name></author><author><name sortKey="Bustamante, Cd" uniqKey="Bustamante C">CD Bustamante</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haber, M" uniqKey="Haber M">M Haber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weissensteiner, H" uniqKey="Weissensteiner H">H Weissensteiner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Geystelen, A" uniqKey="Van Geystelen A">A Van Geystelen</name></author><author><name sortKey="Decorte, R" uniqKey="Decorte R">R Decorte</name></author><author><name sortKey="Larmuseau, Mhd" uniqKey="Larmuseau M">MHD Larmuseau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pemberton, Tj" uniqKey="Pemberton T">TJ Pemberton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fumagalli, M" uniqKey="Fumagalli M">M Fumagalli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zerbino, Dr" uniqKey="Zerbino D">DR Zerbino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amberger, Js" uniqKey="Amberger J">JS Amberger</name></author><author><name sortKey="Bocchini, Ca" uniqKey="Bocchini C">CA Bocchini</name></author><author><name sortKey="Scott, Af" uniqKey="Scott A">AF Scott</name></author><author><name sortKey="Hamosh, A" uniqKey="Hamosh A">A Hamosh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stelzer, G" uniqKey="Stelzer G">G Stelzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pybus, M" uniqKey="Pybus M">M Pybus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabeti, Pc" uniqKey="Sabeti P">PC Sabeti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pickrell, Jk" uniqKey="Pickrell J">JK Pickrell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Danecek, P" uniqKey="Danecek P">P Danecek</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Cingolani, P" uniqKey="Cingolani P">P Cingolani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sherry, St" uniqKey="Sherry S">ST Sherry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karczewski, Kj" uniqKey="Karczewski K">KJ Karczewski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Macarthur, J" uniqKey="Macarthur J">J MacArthur</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quinlan, Ar" uniqKey="Quinlan A">AR Quinlan</name></author><author><name sortKey="Hall, Im" uniqKey="Hall I">IM Hall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mazandu, Gk" uniqKey="Mazandu G">GK Mazandu</name></author><author><name sortKey="Chimusa, Er" uniqKey="Chimusa E">ER Chimusa</name></author><author><name sortKey="Mbiyavanga, M" uniqKey="Mbiyavanga M">M Mbiyavanga</name></author><author><name sortKey="Mulder, Nj" uniqKey="Mulder N">NJ Mulder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bindea, G" uniqKey="Bindea G">G Bindea</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balasubramanian, S" uniqKey="Balasubramanian S">S Balasubramanian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smedley, D" uniqKey="Smedley D">D Smedley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pi Ero, J" uniqKey="Pi Ero J">J Piñero</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Babbi, G" uniqKey="Babbi G">G Babbi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, Ap" uniqKey="Davis A">AP Davis</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Landrum, Mj" uniqKey="Landrum M">MJ 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Gibbs</name><name sortKey="Metcalf, Ginger" sort="Metcalf, Ginger" uniqKey="Metcalf G" first="Ginger" last="Metcalf">Ginger Metcalf</name><name sortKey="Muzny, Donna" sort="Muzny, Donna" uniqKey="Muzny D" first="Donna" last="Muzny">Donna Muzny</name><name sortKey="Rotimi, Charles" sort="Rotimi, Charles" uniqKey="Rotimi C" first="Charles" last="Rotimi">Charles Rotimi</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Dareng, Eileen" sort="Dareng, Eileen" uniqKey="Dareng E" first="Eileen" last="Dareng">Eileen Dareng</name></noRegion></country><country name="Nigeria"><noRegion><name sortKey="Dareng, Eileen" sort="Dareng, Eileen" uniqKey="Dareng E" first="Eileen" last="Dareng">Eileen Dareng</name></noRegion><name sortKey="Adebiyi, Ezekiel" sort="Adebiyi, Ezekiel" uniqKey="Adebiyi E" first="Ezekiel" last="Adebiyi">Ezekiel Adebiyi</name><name sortKey="Adebiyi, Ezekiel" sort="Adebiyi, Ezekiel" uniqKey="Adebiyi E" first="Ezekiel" last="Adebiyi">Ezekiel Adebiyi</name><name sortKey="Falola, Oluwadamilare" sort="Falola, Oluwadamilare" uniqKey="Falola O" first="Oluwadamilare" last="Falola">Oluwadamilare Falola</name><name sortKey="Odia, Trust" sort="Odia, Trust" uniqKey="Odia T" first="Trust" last="Odia">Trust Odia</name></country><country name="Ouganda"><noRegion><name sortKey="Nyangiri, Oscar A" sort="Nyangiri, Oscar A" uniqKey="Nyangiri O" first="Oscar A." last="Nyangiri">Oscar A. Nyangiri</name></noRegion></country><country name="Tunisie"><noRegion><name sortKey="Benkahla, Alia" sort="Benkahla, Alia" uniqKey="Benkahla A" first="Alia" last="Benkahla">Alia Benkahla</name></noRegion></country><country name="Égypte"><noRegion><name sortKey="Kassim, Samar K" sort="Kassim, Samar K" uniqKey="Kassim S" first="Samar K." last="Kassim">Samar K. Kassim</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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